Status:
COMPLETED
Supplementation of Dual Probiotic Strains Reduced Fasting Triglyceride and Enhanced Apolipoprotein A-V Levels
Lead Sponsor:
Yonsei University
Conditions:
Hypertriglyceridemia
Eligibility:
All Genders
24-68 years
Phase:
PHASE3
Brief Summary
The purpose of this study is to evaluate the effect of dual probiotic strains containing Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 on triglyceride and apolipoprotein A-V.
Detailed Description
A randomized, double-blind, placebo-controlled study was conducted on 128 nondiabetic and hypertriglyceridemic (Plasma Triglyceride, 150-500 mg/dL) subjects. Over a 12 week test period, the probiotic ...
Eligibility Criteria
Inclusion
- nondiabetic (plasma fasting glucose, \<126mg/dL; 2-hour plasma glucose, \<200mg/dL)
- borderline to moderate hypertriglyceridemia (plasma triglyceride, 150-500 mg/dL)
Exclusion
- lipid-lowering medications use
- any medications or supplement use
- any probiotics products use for the past 1 months
- dyslipidemia
- diabetes mellitus
- hypertension
- liver disease
- renal disease
- cardiovascular disease
- cerebrovascular disease
- pancreatitis
- cancer
- medication or alcohol abuse
- pregnant or breast feeding
Key Trial Info
Start Date :
June 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2014
Estimated Enrollment :
128 Patients enrolled
Trial Details
Trial ID
NCT02215694
Start Date
June 1 2012
End Date
March 1 2014
Last Update
August 13 2014
Active Locations (1)
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1
Laboratory of Clinical Nutrigenetics/Nutrigenomics
Seoul, South Korea, 120-749