Status:
COMPLETED
Brain Stimulation in Movement Disorders
Lead Sponsor:
Birmingham and Solihull Mental Health NHS Foundation Trust
Collaborating Sponsors:
University of Birmingham
Conditions:
Huntington's Disease
Tourette Syndrome
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Brain stimulation in movement disorders This trial will explore the effects of very gentle electrical stimulation of the brain in patients with movement disorders. Other studies have already been car...
Detailed Description
The procedure does not involve any surgery or hair removal. We simply put a small amount of electrode gel on your head and then hold two electrodes on the top of your head for a short period of time (...
Eligibility Criteria
Inclusion
- Patients will have either Tourette syndrome (TS) diagnosed according to Diagnostic and Statistical Manual of Mental Disorders criteria or Huntington's disease (HD) diagnosed genetically
- Controls will be generally healthy individuals not taking any psychoactive medications and without diagnosed psychiatric or serious medical conditions (e.g. history of seizures, heart disease, head injury)
- 18-65 years of age for TS; 40-65 years of age for HD; 18-65 for controls
- English as a first language
Exclusion
- No current significant co-morbid psychiatric disorder (e.g. learning disability, schizophrenia) or medical condition which may contraindicate brain stimulation or magnetic resonance imaging (e.g. epilepsy, chronic heart disease, scalp skin conditions, metal skull implants). Mild symptoms of obsessive compulsive disorder, attention deficit hyperactivity disorder and/or mood disorders will be accepted as these are very common
- No contraindications to MRI scanning (if they will be scanned) such as metal in the body, claustrophobia or seizure history
- No complex medication regimes (e.g. combinations of multiple dopaminergic drugs plus selective serotonin reuptake inhibitors
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT02216474
Start Date
September 1 2014
End Date
September 1 2019
Last Update
January 22 2020
Active Locations (1)
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1
Department of Neuropsychiatry, BSMHFT The Barberry
Birmingham, West Midlands, United Kingdom, B15 2FG