Status:

UNKNOWN

Initial Study With the CNDS Advanced Cervical Scan to Recalibrate Spectral Data for Use in Future Screening Studies

Lead Sponsor:

Guided Therapeutics

Conditions:

Cervical Disease

Eligibility:

FEMALE

21+ years

Brief Summary

The purpose of this study is to evaluate whether fluorescence and reflectance spectroscopy can improve the ability to detect the presence of premalignant lesions on the cervix.

Detailed Description

Subjects (approximately 500) will be initially enrolled from a general screening population in the first phase, and during the second phase from the colposcopy clinic population (approximately 300) ba...

Eligibility Criteria

Inclusion

  • Age 21 or above
  • Able to read or understand and give informed consent
  • Negative pregnancy test or documentation of acceptable birth control
  • Willing to undergo colposcopy, cytology (if required) and HPV testing on day of study
  • Abnormal cytology result within 120 days of CNDS test for Phase 2 subjects

Exclusion

  • Pregnancy
  • Menstruating
  • Previous cervical neoplasia
  • Prior hysterectomy
  • Conditions relating to the cervix that would render the test difficult to perform, including but not limited to:
  • Excessive blood or mucus that cannot be removed Abnormal congenital cervix Unable to tolerate speculum or CNDS single use cervical guide

Key Trial Info

Start Date :

August 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2015

Estimated Enrollment :

800 Patients enrolled

Trial Details

Trial ID

NCT02217215

Start Date

August 1 2014

End Date

December 1 2015

Last Update

August 15 2014

Active Locations (1)

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Georgia Regents University

Augusta, Georgia, United States, 30912