Status:

COMPLETED

Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous Lesions

Lead Sponsor:

University Hospital Ostrava

Conditions:

Chronic Inflammation of Hypopharynx

Hoarseness

Eligibility:

All Genders

30-80 years

Phase:

NA

Brief Summary

The aim of the project is to compare NBI endoscopy and standard endoscopic method using white light and evaluate accuracy both methods in early detection and diagnosis hypopharyngeal and laryngeal pre...

Detailed Description

Laryngeal squamous cell carcinoma (SCC) is one of the most common head and neck cancers. In many cases laryngeal SCC is diagnosed too late for curative treatment - the reasons are non-specific symptom...

Eligibility Criteria

Inclusion

  • patients in age 30-80 years
  • patients with chronic inflammation of hypopharynx and larynx longer than 3 months (with pain in throat, globbus pharyngeal,…) and/or
  • patients with hoarseness longer than 3 weeks and/or
  • patients with macroscopic laryngeal lesions (leukoplakia, erythroplakia, Reinke oedema, excluded polyps, cystic lesions and nodules)
  • patients with histological confirmation of dysplasia and/or
  • patients with carcinoma in situ/invasive carcinoma of hypopharynx or larynx and/or
  • patients with recurrent respiratory papillomatosis of all ages

Exclusion

  • inability to undergo endoscopic examination

Key Trial Info

Start Date :

February 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2016

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT02217358

Start Date

February 1 2012

End Date

May 1 2016

Last Update

September 8 2016

Active Locations (1)

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University Hospital Ostrava

Ostrava, Moravian-Silesian Region, Czechia, 70852