Status:

COMPLETED

Arterial Stiffness in Type I Diabetes Mellitus

Lead Sponsor:

University of Florida

Collaborating Sponsors:

Diabetes Action Research and Education Foundation

Conditions:

Arterial Stiffness in Youth With Type 1 Diabetes

Eligibility:

All Genders

8-21 years

Brief Summary

Using radial artery tonometry to study arterial stiffness, the plan is to study a cohort of 65 children with Type I diabetes mellitus. This prospective, crossover study will help determine if there is...

Detailed Description

The subject will fast overnight (nothing to eat or drink for at least 8 hours). The subject will be asked to drink a mixed meal replacement drink (Boost) and will be randomized (like flipping a coin) ...

Eligibility Criteria

Inclusion

  • Type 1 diabetes based on clinical history
  • Basal-bolus insulin regimen
  • Duration of diabetes greater than 1 year
  • Blood glucose 65-200 mg/dL fasting

Exclusion

  • Use of metformin or any other hypoglycemic agents besides insulin
  • Use of anti-hypertensives
  • Caffeine or smoking within the past 24 hours

Key Trial Info

Start Date :

October 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2015

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02218268

Start Date

October 1 2014

End Date

August 1 2015

Last Update

February 6 2017

Active Locations (1)

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1

University of Florida

Gainesville, Florida, United States, 32610