Status:
UNKNOWN
Bronchodilator Test in Mechanical Ventilated Chronic Obstructive Pulmonary Disease Patients
Lead Sponsor:
Beijing Chao Yang Hospital
Collaborating Sponsors:
First Affiliated Hospital of Chongqing Medical University
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Investigators developed a test to assess the bronchodilator effects in mechanically ventilated chronic obstructive pulmonary disease patients by comparing the change of airway resistance. No matter wh...
Detailed Description
Bronchodilator is commonly used in mechanical ventilated chronic obstructive pulmonary disease patients. It is assumed that patient's response to bronchodilator is the same during acute exacerbation o...
Eligibility Criteria
Inclusion
- should meet all the criteria:
- Acute exacerbated chronic obstructive pulmonary disease
- Invasive mechanical ventilation with intubation outside ICU no more than 48 hours
Exclusion
- Meet any of the criteria:
- Asthma
- Tracheotomy
- Prolonged Mechanical Ventilation (Have been mechanical ventilated for more than 21 days)
- Unstable hemodynamic status
- Severe pneumonia
- Contraindication for bronchodilator
- Contraindication for sedation
- Refusal to participate in study
- Re-intubation in 48 hours
- Mental disorder, could not understand and accomplish pulmonary function test
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2015
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT02218398
Start Date
May 1 2013
End Date
December 1 2015
Last Update
August 18 2014
Active Locations (1)
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1
Respiratory Intensive Care Unit, Beijing Chaoyang Hospital
Beijing, Beijing Municipality, China, 101100