Status:
COMPLETED
Pilot Study on Pairing Sedation Strategies and Weaning
Lead Sponsor:
MemorialCare Health System
Collaborating Sponsors:
Memorial Medical Center Foundation
Conditions:
Acute Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A three-arm, randomized, pilot study, to assess the feasibility for the analgesia-first sedation (AFS) study arm/intervention (Fentanyl push first). The study will assess additional outcomes for all t...
Detailed Description
A three-arm, randomized, pilot study, to assess the feasibility for the analgesia-first sedation (AFS) study arm/intervention (Fentanyl push first). The study will assess additional outcomes for all t...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- ≥ 18 years of age
- Mechanically ventilated with an expected duration of MV ≥ 48 hours
- ICU team has initiated continuous sedative and/or /analgesic infusions
- Exclusion criteria:
- Admission after resuscitation from cardiac arrest
- Admission with traumatic brain injury or another acute neurologic event (e,g. stroke, uncontrolled seizures).
- History of severe dementia
- Admission because of acute alcohol withdrawal or acute drug intoxication
- Administration of more than 24 hours of continuous sedation
- Allergy to fentanyl, midazolam, and/or propofol
- Lack of informed consent
Exclusion
Key Trial Info
Start Date :
December 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 18 2018
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT02219659
Start Date
December 1 2014
End Date
May 18 2018
Last Update
October 7 2025
Active Locations (1)
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1
Long Beach Memorial Medical Center
Long Beach, California, United States, 90806