Status:

COMPLETED

Oral Triiodothyronine for Infants Less Than 5 Months & Malnourished Children Undergoing Cardiopulmonary Bypass in Indonesia

Lead Sponsor:

National Cardiovascular Center Harapan Kita Hospital Indonesia

Collaborating Sponsors:

CRDF Global

Osypka Germany

Conditions:

Postoperative; Dysfunction Following Cardiac Surgery

Eligibility:

All Genders

1-36 years

Phase:

PHASE3

Brief Summary

Infants and children undergoing cardiac surgery require mechanical support for circulation called cardiopulmonary bypass. The artificial pump ensures that blood flow to the body is maintained during s...

Detailed Description

Methods Study Overview and Objectives We will perform a randomized double blinded placebo controlled trial in Indonesian children under 3 years of age, who are undergoing cardiopulmonary bypass proce...

Eligibility Criteria

Inclusion

  • Children undergoing cardiopulmonary bypass
  • Age 3 years old or less
  • Aristotle score 6 and above
  • Total correction or biventricular repair

Exclusion

  • Single ventricle defects
  • Body weight less than 2 kg at the time of recruitment
  • Presentation with sepsis
  • Tachyarrhythmia or any other arrhythmia before surgery
  • Creatinine level of more than 2 mg/dL
  • Known thyroid disease
  • Known lung abnormalities (incl. infection) before surgery.

Key Trial Info

Start Date :

June 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2015

Estimated Enrollment :

224 Patients enrolled

Trial Details

Trial ID

NCT02222532

Start Date

June 1 2013

End Date

June 1 2015

Last Update

February 17 2016

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Pediatric Cardiac ICU National Cardiovascular Center Harapan Kita

Jakarta, DKI Jakarta, Indonesia, 11420