Status:
UNKNOWN
Immunological Markers Screening for Colorectal Cancer
Lead Sponsor:
State Key Laboratory of Cancer Biology
Collaborating Sponsors:
Shanghai Jiao Tong University School of Medicine
Air Force Military Medical University, China
Conditions:
Colorectal Cancer
Eligibility:
All Genders
18-90 years
Brief Summary
Colorectal cancer incidence is increasing at an alarming rate in China. Recent reports concluded aberrant immunological function was associated with colorectal cancer outcome, however, the influence o...
Eligibility Criteria
Inclusion
- Patient must have a histologically proven adenocarcinoma of colon or rectum cancer.
- Patients must have a performance status of 0,1, or 2 by the Southwest Oncology Group criteria.
- Patients must have recovered from any effects of surgery.
- Evaluable disease must be present outside radiation field. At least 3 weeks must have elapsed after discontinuation of radiation therapy.
- Patients must provide a signed consent to participate in the study.
- Patients must complete all questionnaires.
Exclusion
- Patients with a proven history of peptic ulcer disease or gastroesophageal reflux.
- History of other malignancy, except for cancers that have been treated with a curative intent and patient is without evidence of active disease.
- Unresolved bacterial infection requiring treatment with antibiotics.
- Pregnant or lactating women may not participate in the study.
- Patients known to have HIV-1 virus infection because of the undetermined effect of this chemotherapy regimen in patients with HIV-1 and the potential for serious interaction with anti-HIV medications.
- Gilbert's disease.
- Other serious concurrent infection
- Clinically significant cardiac disease not well controlled with medication (e.g. congestive heart failure, symptomatic coronary artery disease and cardiac arrhythmias) or myocardial infarction within the last 12 months.
Key Trial Info
Start Date :
January 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT02222753
Start Date
January 1 2014
Last Update
August 21 2014
Active Locations (1)
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1
Shanghai Jiaotong University
Shanghai, Shanghai Municipality, China, 200240