Status:
COMPLETED
Alternative Antibiotic Regime in the Treatment of GAgP
Lead Sponsor:
Kocaeli University
Conditions:
Generalized Aggressive Periodontitis
Aggressive Periodontitis
Eligibility:
All Genders
18-35 years
Phase:
PHASE4
Brief Summary
The objective of this randomized clinical study was to evaluate the effect of systemic administration of moxifloxacin compared to amoxicillin plus metronidazole combined with non-surgical treatment in...
Detailed Description
The American Academy of Periodontology and the European Federation of Periodontology were reported that patients with GAgP may have benefit from adjunctive administration of antibiotics. Antibiotics a...
Eligibility Criteria
Inclusion
- The periodontal diagnosis of subjects with GAgP was established on the basis of clinical and radiographic criteria defined by the 1999 International World Workshop for a Classification of Periodontal Diseases and Conditions.
- Patients were included if they were between 18 and 35 years of age and otherwise healthy.
Exclusion
- if the patients had any known systemic diseases or conditions that can/could influence the periodontal status (cancer, cardiovascular and respiratory diseases)
- history of hepatitis or HIV infection,
- immunosuppressive chemotherapy
- current pregnancy, planning a pregnancy or lactation
- requirement for antibiotic prophylaxis
- oral diseases other than GAgP, ongoing orthodontic therapy
- a history of antibiotic therapy or periodontal treatment within the preceding six months.
- Subjects were excluded if they had known allergies to quinolones or penicillin or metronidazole
- Not willing to participate to the study.
- Not accept to sign written informed consent
Key Trial Info
Start Date :
May 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2014
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT02223702
Start Date
May 1 2011
End Date
July 1 2014
Last Update
November 2 2018
Active Locations (1)
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1
Kocaeli University Faculty of Dentistry Department of Periodontology
Kocaeli, Turkey (Türkiye), 41190