Status:
COMPLETED
The Effect of Dexmedetomidine on Brachial Plexus Block for Shoulder Surgery
Lead Sponsor:
Women's College Hospital
Conditions:
Nerve Pain
Shoulder Pain
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine whether a small dose of Dexmedetomidine, when given either intravenously or as part of the interscalene nerve block solution, prolongs pain relief following s...
Detailed Description
Unilateral shoulder surgical procedures, including acromioplasty, rotator cuff repair and Bankart procedure generally allow the patient to go home the same day. However, post-surgical pain is often se...
Eligibility Criteria
Inclusion
- unilateral surgical shoulder procedures under general anesthetic
- English speaking patients
- ASA I-III patients
- BMI \<38 kg/m2
Exclusion
- proximal clavicular surgery
- preexisting neurological deficits or peripheral neuropathy
- known coronary heart disease, congestive heart failure, cardiomyopathies, or arrhythmias
- known cerebrovascular disease
- baseline heart rate \<60 beats per minute or baseline systolic blood pressure \<100 mm Hg
- medications that reduce heart rate (as beta-blockers, calcium blockers) known liver dysfunction or existing diseases known to cause hepatic or renal impairment
- severe bronchopulmonary disease
- local infection
- contra-indication to regional anesthesia (bleeding, coagulopathy)
- chronic pain disorders
- current use of over 30mg oxycodone or equivalent per day
- contraindication to a component of multimodal analgesia
- allergy to local anesthetics or dexmedetomidine
- history of significant psychiatric conditions that may affect patient assessment
- pregnancy
- inability to provide consent
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2015
Estimated Enrollment :
99 Patients enrolled
Trial Details
Trial ID
NCT02225054
Start Date
May 1 2013
End Date
March 1 2015
Last Update
November 6 2017
Active Locations (1)
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1
Women's College Hospital
Toronto, Ontario, Canada, M5S 1B2