Status:
COMPLETED
The Focal Electro-Oculogram in Macular Disease
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Macular Degeneration
Age-Related Macular Degeneration
Eligibility:
All Genders
10-100 years
Brief Summary
Background: \- Maculopathies are eye conditions that affect the center of the retina. Retina health depends on the retinal pigment epithelium (RPE), a layer behind the retina. A new test may measure ...
Detailed Description
OBJECTIVE: The objective of this protocol is to investigate the local response of the retinal pigment epithelium (RPE) across the posterior pole of the eye by recording the focal electrooculogram (EO...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Participant must be 10 years of age or older.
- Participant (or legal guardian) must understand and sign the protocol s informed consent document.
- Participant must be able to cooperate with the testing required for this study.
- For Participants with macular disease only:
- Participant must have macular disease, defined as evidence of loss of centrally mediated retinal dysfunction and/or degeneration as established by standard clinical methods including perimetry, ERG and imaging.
- Participant must have a measurable visual acuity.
- For Healthy Volunteers only:
- Participant must have visual acuity of 20/20 or better in at least one eye.
- EXCLUSION CRITERIA:
- 1\) Participant with pre-retinal media opacities that would prevent focal light presentation.
Exclusion
Key Trial Info
Start Date :
February 6 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 28 2020
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT02225119
Start Date
February 6 2015
End Date
February 28 2020
Last Update
December 11 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892