Status:
TERMINATED
SNPeCPR In Cardiac Arrest REsuscitation
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Cardiopulmonary Arrest
Eligibility:
All Genders
18-75 years
Phase:
PHASE3
Brief Summary
Approximately 50,000 patients are victims of out of hospital cardiac arrest every year in France. Despite cardiopulmonary resuscitation (CPR) and many studies on the topic resuscitation survival after...
Detailed Description
1. OBJECTIVES The objective of this study is to demonstrate the superiority of Sodium nitroprusside enhanced cardiopulmonary resuscitation (SNPeCPR) on optimized standard cardiopulmonary resuscitation...
Eligibility Criteria
Inclusion
- Patient with out of hospital cardiac arrest
- Age\> 18 years and \<75 years
- Initial Rhythm: Ventricular fibrillation or ventricular tachycardia or pulseless electrical activity
Exclusion
- out of hospital cardiac arrest of non-cardiac origin:
- trauma
- anoxic, including drowning
- hemorrhage,
- overdose (drugs),
- drug,
- electric
- Do Not Resuscitate Order,
- obvious signs of clinical death (decomposition, cadaveric rigidity, decapitation)
- recent sternotomy (\<6 months or recent scar)
- Contraindications related to sodium nitroprusside
- Women of childbearing age (between 18 and 55 years)
- Other contra-indications will usually not known during resuscitation in case of presence of a relative rescue team must be searched: Hypothyroidism, Sulfuryl transferase deficiency (rhodanese Lang) currently recognized in patients with Leber optic atrophy, tobacco amblyopia or severe hepatic impairment.
- Obesity
Key Trial Info
Start Date :
January 2 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 2 2018
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT02225561
Start Date
January 2 2015
End Date
January 2 2018
Last Update
January 10 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
SMUR - Hôpital Lariboisière
Paris, France, 75010