Status:
COMPLETED
Multi-center Study of Residual Neuromuscular Block Incidence in the Post-anesthesia Care Unit
Lead Sponsor:
University of Valencia
Collaborating Sponsors:
General University Hospital of Valencia
Hospital General Universitario Gregorio Marañon
Conditions:
Incomplete Reversal of Neuromuscular Block
Postoperative Respiratory Complications
Eligibility:
All Genders
18+ years
Brief Summary
Residual neuromuscular block (RNMB) is frequent in the immediate postoperative period and is a source of complications, mainly respiratory. The incidence is variable due to multiple factors. In Spain ...
Detailed Description
Residual neuromuscular block (RNMB) is frequent in the immediate postoperative period and is a source of complications, mainly respiratory. This includes recovery delay or hospital discharge delays, r...
Eligibility Criteria
Inclusion
- Patients \>18 years-old
- General anesthesia with non-depolarizing NMBA
- Transferred extubated on spontaneous ventilation to the PACU
Exclusion
- American Society of Anesthesiologists physical status IV-V
- emergency and cardiac surgery
- patients unable to respond adequately at the moment of pre- or postoperative evaluation (psychiatric diseases, excessive somnolence, agitation, etc.)
- noncompensated diabetes mellitus or diabetic neuropathy
- symptomatic severe hypothyroidism (or untreated), or scheduled for total thyroidectomy
- chronic or acute renal insufficiency
- severe hepatopathy (Child-Pugh B, C)
- intraoperative blood transfusion \>3 blood units
- intraoperative maintained arterial hypotension
- arrival to the PACU intubated or with instrumented airway (including surgical)
- pre- or perioperative drugs intake affecting the neuromuscular transmission
- neuromuscular diseases affecting the physiology of the neuromuscular system
Key Trial Info
Start Date :
June 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2014
Estimated Enrollment :
763 Patients enrolled
Trial Details
Trial ID
NCT02226809
Start Date
June 1 2014
End Date
July 1 2014
Last Update
August 27 2014
Active Locations (25)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital General de Elda
Elda, Alicante, Spain, 03600
2
Hospital de Bellvitge
Badalona, Barcelona, Spain, 08907
3
Hospital Universitario Germans Trias i Pujol
Badalona, Barcelona, Spain, 08916
4
Hospital Clinic Universitari
Barcelona, Barcelona, Spain, 08036