Status:
COMPLETED
Treatment for Teens With Alcohol Abuse and Depression
Lead Sponsor:
Duke University
Collaborating Sponsors:
UConn Health
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions:
AOD Use, Abuse, and Dependence
Depression
Eligibility:
All Genders
13-263 years
Phase:
NA
Brief Summary
The investigators will recruit adolescents with alcohol or cannabis abuse and clinically significant depression. All participants will receive 12 sessions of an evidence-based treatment for alcohol ab...
Detailed Description
Alcohol and other substance use disorders (AOSUDs), primarily cannabis use disorders, continue to be a significant public health concern among American adolescents. AOSUDs are commonly accompanied by ...
Eligibility Criteria
Inclusion
- Age 13 years to 21 years, 11 months at baseline
- Current alcohol or cannabis abuse or dependence diagnosis (DSM-IV) OR current level of potentially harmful drinking or cannabis use as evidenced by (1) consumption of 4 or more drinks per drinking day (males) or three or more (females), or use of cannabis at least three times in past 90 days (or before admission into a controlled environment)
- Current clinically significant depression, defined as a score of 40 or more on the Children's Depression Rating Scale-Revised at baseline
- If currently taking anti-depressant medication, on a stable dose for at least one month
- Willingness to accept treatment
- Able to speak and read English (5th-grade level)
- Residence within 45-minute drive from treatment site
- Adolescent and a parent agree to sign Institutional Review Board approved consent/assent form; for subjects ages 18-19, parent involvement is optional and is the decision of the youth
- Parent/guardian agrees to provide collateral information and to designate two third parties who could be contacted in case the subject is lost to follow-up; for subjects ages 18-19, the participating youth will provide this information
- Participant (and parent, if youth is under age 18) not planning to move outside the area in the next 9 months.
Exclusion
- Suicidal ideation with a plan, or suicide attempt within 30 days. In addition to such suicide risk being indicated in baseline interview material, a score exceeding the 89th percentile on the Suicide Ideation Questionnaire (SIQ-Jr), will necessitate an immediate risk assessment by the Independent Evaluator which may lead to exclusion under this criterion.
- Homicidal ideation with a plan or any plan to hurt others
- Lifetime diagnosis of psychosis, schizophrenia, bipolar disorder, intellectual disability or autistic disorder
- Current dependence on a substance other than alcohol, marijuana or nicotine
- Current non-alcohol or cannabis use disorder or depression primary diagnosis, i.e., the diagnosis requires care more urgently than does alcohol or cannabis use disorder or depression
Key Trial Info
Start Date :
January 16 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 3 2020
Estimated Enrollment :
103 Patients enrolled
Trial Details
Trial ID
NCT02227589
Start Date
January 16 2015
End Date
January 3 2020
Last Update
February 5 2020
Active Locations (2)
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1
University of Connecticut Health Center
Farmington, Connecticut, United States, 06030-3926
2
Duke Child and Family Study Center
Durham, North Carolina, United States, 27705