Status:
ACTIVE_NOT_RECRUITING
Magnetic Resonance Elastography in Hydrocephalus
Lead Sponsor:
Dartmouth-Hitchcock Medical Center
Collaborating Sponsors:
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Conditions:
Hydrocephalus
Eligibility:
All Genders
45-95 years
Phase:
NA
Brief Summary
The purpose of this project is to assess the utility of a new magnetic resonance technique called magnetic resonance elastography (MRE) in the non-invasive diagnosis of normal pressure hydrocephalus. ...
Eligibility Criteria
Inclusion
- Age \>21;
- One or more of the following complaints: memory loss/dementia, urinary incontinence, or progressive gait disturbance
- Ventriculomegaly defined as temporal horn width \>2 mm or a FH:ID ratio\>30% on computed tomography or MRI, where FH is the maximal distance between the frontal horns and ID is the internal diameter from inner table to inner table of the skull at this level (Greenberg)
- A diagnosis of any adult onset hydrocephalus (NPH, post-traumatic, post-hemorrhagic, obstructive, or idiopathic) will be considered for enrollment in this study
Exclusion
- Implanted neuro-stimulator or cardiac pacemaker
- Known coagulopathy; major organ dysfunction
- End-stage congestive heart failure
- Oxygen-dependent pulmonary disease, hepatic cirrhosis, or dialysis- dependent renal failure; or other condition which, according to the assessment of the treating surgeon or anesthesia team
- Precludes consideration of elective surgery
- Patients who may be pregnant will be excluded from this study as well
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2027
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT02230124
Start Date
March 1 2007
End Date
December 30 2027
Last Update
April 27 2025
Active Locations (1)
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1
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756