Status:
COMPLETED
Trigeminal Endonasal Perception: A Predictor for Septoplasty Outcome
Lead Sponsor:
University of Zurich
Conditions:
Empty Nose Syndrome
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
This study investigates wether patients with increased trigeminal perception threshold and low expression of TRP channels have more often nasal blockage despite functionally successful nasal surgery (...
Detailed Description
The aim of this study is to find out wether patients with high trigeminal perception threshold (=decreased intranasal sensibility) and low expression of TRP channels of the mucosa suffer more often fr...
Eligibility Criteria
Inclusion
- Patients undergoing a primary septoplasty and/or turbinoplasty
- Patients suffering from empty nose syndrome after measurably successful nasal surgery
- Patients with removed turbinates and/or septum, not suffering from ENS (i.e. tumor patients)
Exclusion
- Patients with known neurologic disorders that could compromise perception threshold measurements
- Patients with known allergies/intolerance to test agents that are used to measure perception thresholds (Cineol=Eucalypt; Menthol, CO2= Carbon Dioxide)
- Inability to judge or understand the testing or the informed consent
Key Trial Info
Start Date :
May 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2018
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT02230423
Start Date
May 1 2015
End Date
May 1 2018
Last Update
October 12 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Zurich University Hospital
Zurich, Switzerland, 8091