Status:

COMPLETED

Cardiopulmonary Adaptation of Short Term Exposure to High Altitude in Fontan Patients: Swiss Fontan & ALtitude COllaboratioN (FALCON) Study

Lead Sponsor:

Insel Gruppe AG, University Hospital Bern

Collaborating Sponsors:

Mach Gaensslen Foundation

Conditions:

Fontan Procedure

Altitude

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Important advances in cardiac surgery, intensive care, and diagnostic modalities over the last decades have led to a steady growth in the number of adults with congenital heart defects. Among adults w...

Detailed Description

Background: Important advances in cardiac surgery, intensive care, and diagnostic modalities over the last decades have led to a steady growth in the number of adults with congenital heart defects (G...

Eligibility Criteria

Inclusion

  • Age above 18years
  • Congenital heart disease and Fontan circulation
  • NYHA functional class I \& II
  • Peak VO2 \> 45% of predicted
  • Signed informed consent

Exclusion

  • "Failing Fontan", peak VO2 \< 45% of predicted
  • Significant right-to-left shunt
  • Baseline arterial O2 saturation at rest \<90% at room air
  • Hospitalization within the last 3 months for cardiac reasons
  • Decrease in functional NYHA class within the last 3 months
  • Motor skill inability to perform a maximal exercise stress test
  • Respiratory Exchange Ratio \< 1
  • Pregnancy

Key Trial Info

Start Date :

July 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2014

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT02237274

Start Date

July 1 2014

End Date

December 1 2014

Last Update

February 23 2015

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Department of Cardiology, GUCH, Bern University Hospital

Bern, Switzerland, 3010