Status:

COMPLETED

Detection of Brown Adipose Tissue by Magnetic Resonance Imaging

Lead Sponsor:

University of North Carolina, Chapel Hill

Collaborating Sponsors:

North Carolina Translational and Clinical Sciences Institute

Conditions:

Obesity

Brown Adipose Tissue

Eligibility:

All Genders

18+ years

Brief Summary

The primary goal of this study is to assess the accuracy of conventional fat fraction proton MRI for the detection of Brown Adipose Tissue (BAT) in healthy subjects using \[18F\]-2-fluoro-2-deoxy-D-gl...

Detailed Description

In the fight against obesity, brown adipose tissue (BAT) is considered to be the newest target. The hypothesis is that this tissue is partially responsible for the imbalance between energy intake and ...

Eligibility Criteria

Inclusion

  • Each subject must be fully informed and have signed consent.
  • BMI \< 34
  • Normal neurological and psychological development / able to give consent
  • Willingness to participate in this study

Exclusion

  • Subjects less than 18 years of age
  • Severe claustrophobia
  • Women who are pregnant, nursing an infant or planning to become pregnant in the next 30 days
  • People who have a condition that makes MRI unsafe for them (for example, cardiac pacemaker, epicardial pacemaker leads, cochlear implants, metal aneurysm clip, iron filings in your eyes or metal halo devices)
  • Have had radiation therapy or chemotherapy in the 2 months prior to PET scan
  • Subjects are taking medications that may interfere with BAT detection

Key Trial Info

Start Date :

January 20 2015

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 27 2015

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT02237872

Start Date

January 20 2015

End Date

August 27 2015

Last Update

October 1 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Biomedical Research Imaging Center

Chapel Hill, North Carolina, United States, 27599-7513

2

Biomedical Research Imaging Center

Chapel Hill, North Carolina, United States, 27599

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