Status:
WITHDRAWN
Diagnostics for the Treatment of Progressive Mucosal Lesions of the Oral Cavity: a Prospective Study
Lead Sponsor:
Maastricht University Medical Center
Conditions:
Chromosomal Instability
Low Grade Dysplasia Oral Cavity
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Despite improvements in therapy, head and neck carcinomas still have a poor prognosis with a 5-year survival of \~ 50%. Malignancies of the head and neck area are (almost) always preceded by precursor...
Eligibility Criteria
Inclusion
- subjects ≥18 years
- premalignant lesions of the oral cavity, classified as hyperkeratosis, hyperplasia, mild or moderate dysplasia
- written informed consent
Exclusion
- former malignancy or lesion classified as severe dysplasia or carcinoma in situ at the same anatomical localization of the oral cavity
- lesions within an anatomical field which has been exposed to former treatment (e.g. radiotherapy)
- insufficient biopsy material to perform additional FISH analysis
- pregnancy, because of the physical burden (e.g. extra general anesthesia) in this study setting
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2024
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT02238574
End Date
December 1 2024
Last Update
January 9 2018
Active Locations (1)
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1
Maastricht Universitair Medisch Centrum (MUMC)
Maastricht, Limburg, Netherlands, 6202