Status:
COMPLETED
Chemotherapy Induced Peripheral Neuropathy. Could Physical Therapy Help Treat Symptoms?
Lead Sponsor:
CancerCare Manitoba
Collaborating Sponsors:
University of Manitoba
Conditions:
Breast Cancer
Peripheral Neuropathy, Secondary to Drugs or Chemicals
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The cause of Chemotherapy-Induced Peripheral Neuropathy (CIPN) is still unknown. An estimated 55-60% of patients will experience lasting symptoms affecting function for years post-treatment. Physical ...
Detailed Description
A common side effect is chemotherapy induced peripheral neuropathy (CIPN). CIPN is a small fibre sensory neuropathy that develops in the hands/feet and worsens with increasing dose and duration of tre...
Eligibility Criteria
Inclusion
- Patients diagnosed with stage I-III breast cancer undergoing regular docetaxel treatment either docetaxel-cyclophosphamide (TC) or 5FU-epirubicin-cyclophosphamide-docetaxel (FEC-D).
- Patients that have not had chemotherapy in the past and do not have identified risk factors (listed below in the exclusion criteria).
- All patients must be able to communicate in english or be able to have a translator present at all appointments.
Exclusion
- Patients diagnosed with stage IV breast cancer or who have co-morbid conditions that are known to cause peripheral neuropathic symptoms, including previous chemotherapy, exposure to toxins (such as lead), Diabetes, Shingles, B12 deficiency, Alcoholism, Lyme disease, Syphilis, HIV, Hereditary disorders such as Charcot-Marie Tooth.
- Patients not planned to receive Docetaxel therapy.
- Patients who cannot communicate in English and unable to bring an interpreter will also be excluded.
Key Trial Info
Start Date :
December 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2017
Estimated Enrollment :
61 Patients enrolled
Trial Details
Trial ID
NCT02239601
Start Date
December 1 2014
End Date
November 1 2017
Last Update
October 9 2019
Active Locations (1)
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1
Rehabilitation Hospital, Health Sciences Centre, 800 Sherbrook St
Winnipeg, Manitoba, Canada, R3A 1M4