Status:
COMPLETED
Effect of Levodopa on Postural Motor Learning in Parkinson Disease
Lead Sponsor:
VA Office of Research and Development
Collaborating Sponsors:
Oregon Health and Science University
Conditions:
Parkinson Disease
Eligibility:
All Genders
18-90 years
Brief Summary
The primary goal of this project is to gain a better understanding of whether and how levodopa (a common anti-Parkinson disease medication) alters postural motor learning in people with Parkinson dise...
Eligibility Criteria
Inclusion
- Between 18 and 90 years of age.
- Individuals with Parkinson Disease
- Healthy adults age-matched to PD participants
- Participants with PD will be currently taking dopamine replacement (i.e. Levodopa)
Exclusion
- All subjects exclusion criteria:
- Deep brain stimulation
- Recent (within 6 months) orthopedic injuries influencing standing or balance
- Inability to stand independently
- Transcranial magnetic stimulation exclusion criteria (for the subset of individuals taking part in the Transcranial Magnetic Stimulation portion of the study):
- History of epilepsy or currently taking any epileptic medication,
- History of seizures
- Family history of epilepsy or seizures
Key Trial Info
Start Date :
August 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2016
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT02239978
Start Date
August 1 2014
End Date
September 1 2016
Last Update
February 23 2017
Active Locations (3)
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1
Oregon Health & Science University
Portland, Oregon, United States, 97210
2
VA Portland Health Care System, Portland, OR
Portland, Oregon, United States, 97239
3
VA Salt Lake City Health Care System, Salt Lake City, UT
Salt Lake City, Utah, United States, 84148