Status:

COMPLETED

Prevention of Necrotizing Enterocolitis of Premature Newborns Under Less Than 1500 g Using Probiotics

Lead Sponsor:

Coordinación de Investigación en Salud, Mexico

Conditions:

Infectious Diseases

Eligibility:

All Genders

27-34 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the incidence of necrotizing enterocolitis and its effect over the secreting immunoglobulin A in the feces with the use of probiotics of the strain Lactobacill...

Detailed Description

Randomized controlled trial, in the Neonatal department of Highly Specialized Medical Unit (UMAE) of Hospital Pediatric - Gynecology No. 48 of Mexican Institute of Social Security (IMSS ) on Leon, Mex...

Eligibility Criteria

Inclusion

  • All of the premature newborns of 34 weeks of gestational age, and with a weight between 700 to 1500 g. that are admitted in the Neonatal Intensive Care Unit or the Neonatology Department that have no contraindication for oral intake in the first 7 days of life. Must not have been diagnosed of sepsis of early onset, prenatal asphyxia, patent ductus arterious with hemodynamic repercussion, major congenital malformations. In all cases the parents or legal guardian must sign the informed consent.

Exclusion

  • All preterm newborns younger than 34 weeks of gestational age that develop any disease different of (NEC) that require to stop the enteral feeding for more than seven days or whose parents or legal guardians revoke the informed consent form.

Key Trial Info

Start Date :

December 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2015

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT02245815

Start Date

December 1 2013

End Date

July 1 2015

Last Update

January 28 2021

Active Locations (1)

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University of Guanajuato School of Medicine

León, Guanajuato, Mexico, 37000