Status:
UNKNOWN
Surgical Ablation of Long-standing Persistent AF During CABG
Lead Sponsor:
Meshalkin Research Institute of Pathology of Circulation
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18-75 years
Phase:
PHASE3
Brief Summary
Purpose. Comparison of outcomes in patients underwent CABG combined with left atrial and biatrial radiofrequency ablation of long-standing persistent atrial fibrillation. Hypothesis of the study - pa...
Detailed Description
This is a single blinded prospective randomized study involving 116 patients with long-standing persistent AF and coronary artery disease. 116 patients are required to have a 80% chance of detecting, ...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- American College of Cardiology (ACC)/ American Heart Association (AHA) Indications for CABG
- At least 2 ECG-verified (12-channel ECG, Holter telemetry) long-term persistent AF within last 12 months
- The patient's consent to participate in the study
- Exclusion Criteria:
- Intolerance of antiarrhythmic drugs
- Heart valve disease requiring invasive treatment
- Left atria more than 6.5 cm
- Prior cardiac surgery
- Active pacemaker treatment
- Active anti-arrhythmic treatment (AAD) class I and III
- Contraindication to oral anticoagulant/heparin treatment
- Ejection fraction less than 30 % (EF \< 30 %) assessed by transthoracic echocardiography
Exclusion
Key Trial Info
Start Date :
December 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2017
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT02246790
Start Date
December 1 2014
End Date
December 1 2017
Last Update
November 13 2015
Active Locations (1)
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1
Meshalkin State Research Institute of Circulation Pathology
Novosibirsk, Russia, 630055