Status:
UNKNOWN
Telomere Length and Other Parameters of Telomere Dysfunction in PSC and Colitis
Lead Sponsor:
Meir Medical Center
Conditions:
Primary Sclerosing Cholangitis
Inflammatory Bowel Disease
Eligibility:
All Genders
18-80 years
Brief Summary
PSC is a chronic cholestatic disorder. The investigators intend to study some telomere parameters and telomere length in order to predict a premalignant state.
Detailed Description
Primary sclerosing cholangitis (PSC) and colitis are chronic inflammatory disorders with malignant potential. Telomerase is an enzyme complex that lengthens telomeres and has enhanced expression in nu...
Eligibility Criteria
Inclusion
- informed consent
- documented PSC and inflammatory bowel disease
Exclusion
- under 18 years, above 80 y
- known active malignancy
- decompensated cirrhosis
- patients who cannot sign informed consent
Key Trial Info
Start Date :
February 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2014
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02247622
Start Date
February 1 2012
End Date
September 1 2014
Last Update
September 25 2014
Active Locations (1)
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1
Meir Medical Center
Kfar Saba, Israel