Status:
COMPLETED
COPD AND ASSESSMENT OF RADIOLABELED AEROSOL DURING NONINVASIVE VENTILATION
Lead Sponsor:
Daniella Cunha Brandao
Collaborating Sponsors:
Universidade Federal de Pernambuco
Conditions:
COPD
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Background: Beneficial effects from noninvasive ventilation (NIV) in acute COPD are well-established, but couple to nebulization is still challenging. Aim: To compare radioaerosol pulmonary deposition...
Eligibility Criteria
Inclusion
- Inclusion criteria were considered as follows: moderate to severe stable COPD (50% ≤ FEV1 \< 80% from predicted values or 30% ≤ FEV1 \< 50% from predicted values)(4); none exacerbation in the last six months; age between 18 - 60 years; both sexes; no smoking history; able to understand verbal commands, and consent to participate in this protocol.
Exclusion
- Presence of dyspnea; cardiopulmonary diseases (chronic obstructive pulmonary disease, pneumonia, cardiac failure, myocardial infarction, pneumothorax); hyperthermia; hemodynamic instability (heart rate \> 150 bpm and systolic blood pressure \< 90 mmHg); arrhythmia absence; pregnancy; and contraindications for use of NIV (29).
Key Trial Info
Start Date :
January 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2013
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT02247856
Start Date
January 1 2013
End Date
March 1 2013
Last Update
September 25 2014
Active Locations (1)
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1
Hospital das Clínicas de Pernambuco
Recife, Pernambuco, Brazil, 50670-901