Status:
COMPLETED
Can Capillary Refill Time Variation During Passive Leg Raising Predict Fluid Responsiveness
Lead Sponsor:
Hopital Louis Pradel
Conditions:
Circulatory Failure
Eligibility:
All Genders
18+ years
Brief Summary
Fluid responsiveness in a context of circulatory failure can be assessed by different way. Microcirculatory evaluation to assess fluid responsiveness could be interesting, but the available device are...
Eligibility Criteria
Inclusion
- The patient is equipped with an arterial and a central venous catheter
- Capillary refill time is measurable.
- A cardiac output monitoring is available
- A 500 ml fluid load as been prescribed by the intensivist in charge.
- A circulatory failure is present defined as follow:
- Patient treated with inotropic or vasoconstrictive drugs
- OR
- Patient presenting an hypotension defined by systolic arterial pressure less than 90 mmHg or mean arterial pressure less than 70 mmHg or a drop 40 mmHg in case of previous Hypertension.
- WITH
- tissue hypoperfusion defined by at least one of the following item:
- Lactate \> 1 mmol/L
- Capillary refill time \> 3 s
- Blotch
- Organ dysfunction due to the circulatory failure (oligo anuria, acute lung injury / acute respiratory distress syndrome, encephalopathy)
Exclusion
- Pregnant woman
- Cardiogenic pulmonary edema
- Circulatory support : extracorporal life support / extracorporal membrane oxygenator, Thoratec, heart mate.
- Moribund patient
- Intra-abdominal hypertension
- Lower limb amputation
Key Trial Info
Start Date :
September 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2017
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT02248025
Start Date
September 1 2014
End Date
May 1 2017
Last Update
May 5 2017
Active Locations (1)
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1
Hôpital Cardiologique Louis Pradel Service d'anesthésie réanimation
Bron, France, 69500