Status:
TERMINATED
A Comparison of Anaesthetic Methods for Total Knee Replacement Surgery
Lead Sponsor:
University Hospital Plymouth NHS Trust
Conditions:
Total Knee Replacement
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
Open-labelled, randomised controlled trial. Patients will be assessed pre-operatively, at 24 and 48 hours for the primary outcome and secondary outcomes (except for Oxford Knee Score which will be ass...
Detailed Description
We are comparing a continuous adductor canal block with a low concentration continuous femoral nerve block. We currently use a low dose femoral nerve catheter based technique as part of our standard t...
Eligibility Criteria
Inclusion
- Subject has a diagnosis of rheumatoid or osteoarthritis and listed for a primary total knee replacement.
- Participant is willing and able to give informed consent for participation in the study.
- Male or Female, aged between 18 and 85 years.
- American Society of Anesthesiologists (ASA) score I-III
- Able (in the clinical staff's opinion) and willing to comply with all study requirements.
- Willing to allow his or her General Practitioner and consultant, if appropriate, to be noti-fied of participation in the study.
Exclusion
- Patient refusal
- Chronic pain (defined as consumption of \>480mg codeine/24hrs or ANY regular strong opiate consumption by the oral/transdermal route)
- Patients aged \<18 or \>85
- ASA score \>III
- Body mass index (BMI) \>35
- Lacking mental capacity to give consent to enter trial/undergo surgery
- Contraindications to catheter placement (coagulopathy , systemic sepsis or infection at placement site, pre-existing neuropathy) or any other component to the study treatment pathway.
- Participant who is terminally ill
- Allergy/intolerance to study medications
- Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study.
Key Trial Info
Start Date :
December 8 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 27 2017
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT02249481
Start Date
December 8 2015
End Date
June 27 2017
Last Update
September 6 2019
Active Locations (1)
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1
Plymouth Hospitals NHS Trust
Plymouth, Devon, United Kingdom, PL6 8BQ