Status:
TERMINATED
The Goal dIrected perFusion Trial in Cardiac Surgery
Lead Sponsor:
IRCCS Policlinico S. Donato
Conditions:
Acute Kidney Injury
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
Previous studies (1-5) have demonstrated that oxygen delivery (DO2) and carbon dioxide production (VCO2) during cardiopulmonary bypass (CPB) are associated with renal outcome in cardiac surgery. The c...
Detailed Description
2\. Study design Multicenter, international, prospective, randomized and controlled study. Patient population 1. Inclusion criteria: Adult (\> 18 years) patients undergoing cardiac operations with CP...
Eligibility Criteria
Inclusion
- Patients undergoing cardiac operations with CPB. Expected CPB duration \> 90 minutes.
Exclusion
- Exclusion criteria: severe chronic renal failure (dialysis or serum creatinine \> 3.0 mg/dL); emergent (must be operated immediately) procedure; moderate-severe anemia (preoperative HCT \< 32%); expected nadir CPB temperature \< 32 °C.
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2017
Estimated Enrollment :
350 Patients enrolled
Trial Details
Trial ID
NCT02250131
Start Date
October 1 2014
End Date
January 1 2017
Last Update
November 24 2023
Active Locations (1)
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1
IRCCS Policlinico San Donato
San Donato Milanese, MI, Italy, 20097