Status:
COMPLETED
Randomized Study of Immune Response to Licensed Influenza Vaccines in Children and Adolescents
Lead Sponsor:
Marshfield Clinic Research Foundation
Collaborating Sponsors:
Centers for Disease Control and Prevention
University of Wisconsin, Madison
Conditions:
Immune Response to Influenza Vaccine
Influenza A Virus Infection
Eligibility:
All Genders
5-17 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to assess the serologic and cell-mediated immune response to licensed live attenuated influenza vaccine (LAIV) and inactivated influenza vaccine (IIV) in children 5-17 yea...
Detailed Description
All children will have baseline blood samples drawn and will then be vaccinated with licensed and approved influenza vaccines. Following the recommendation from the Advisory Committee on Immunization ...
Eligibility Criteria
Inclusion
- Aged 5-17 years for the duration of the study period (Sept 1, 2014-Apr 1, 2015)
- Enrolled in either the immune response study or the vaccine effectiveness study conducted at the site in the 2013-14 influenza season
- If enrolled in the vaccine effectiveness study the previous season must have either been vaccinated and infected with influenza or unvaccinated and uninfected with influenza
Exclusion
- Children with contraindications to either the quadrivalent live attenuated influenza vaccine or to the trivalent inactivated influenza vaccine will be excluded.
- Anyone unwilling or unable to complete all required study activities including informed consent
- Subjects who already received the influenza vaccine for the 2014-15 season
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
131 Patients enrolled
Trial Details
Trial ID
NCT02250274
Start Date
September 1 2014
End Date
April 1 2015
Last Update
April 26 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Marshfield Clinic - Marshfield Center
Marshfield, Wisconsin, United States, 54449