Status:

RECRUITING

OCT Angiography in Wet AMD

Lead Sponsor:

Oregon Health and Science University

Conditions:

Neovascular (Wet) Age-related Macular Degeneration (AMD)

Eligibility:

All Genders

50-100 years

Brief Summary

The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. diagnose the presence of new blood vessels in wet age-related macular degenerat...

Eligibility Criteria

Inclusion

  • Inclusion Criteria (Groups with wet AMD):
  • Adults aged 50 and older with clinical findings of treatment-naïve (never treated) neovascular AMD with active new blood vessel growth confirmed by clinical testing will be considered
  • Inclusion Criteria (Group with healthy eyes)
  • No evidence of retinal disease
  • Refractive error greater than +3.00 diopters or -7.00 diopters (glasses Rx)
  • No recent eye surgery in the last 4 months
  • No significant cataract to interfere with the quality of the imaging
  • Exclusion Criteria (All Groups):
  • Inability to give informed consent
  • Significant kidney disease
  • Blood pressure greater than 180/110
  • Previous macular laser treatment
  • Inability to maintain stable fixation during OCT imaging
  • Visual acuity worse than 20/200

Exclusion

    Key Trial Info

    Start Date :

    September 1 2014

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2026

    Estimated Enrollment :

    160 Patients enrolled

    Trial Details

    Trial ID

    NCT02253030

    Start Date

    September 1 2014

    End Date

    December 1 2026

    Last Update

    February 12 2024

    Active Locations (1)

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    Casey Eye Institute, Oregon Health & Science University

    Portland, Oregon, United States, 97239