Status:
WITHDRAWN
Inhaled Hypertonic Saline for Bronchiolitis
Lead Sponsor:
Queen's University
Conditions:
Bronchiolitis
Eligibility:
All Genders
4-24 years
Phase:
NA
Brief Summary
Study Design: This randomized, double blind, controlled, multi-centre study will occur in the Emergency Department, hospital-based Urgent Care Centre or paediatric outpatient clinics (collectively "ED...
Detailed Description
Children under age 2 years presenting for unscheduled care to the ED with a diagnosis of moderately severe bronchiolitis (as defined by inclusion/exclusion criteria below) will be approached for entry...
Eligibility Criteria
Inclusion
- Age under 2 years
- History of viral upper respiratory infection within previous 7 days
- Wheezing or crackles detected on chest auscultation
- Respiratory Distress Assessment Instrument (RDAI) score of 4 or greater or oxygen saturation (SaO2) of 94% or less in room air.
Exclusion
- History of immunodeficiency, chronic cardiopulmonary disease (other than past history of wheezing), Down syndrome, gestational age under 34 weeks.
- Severe illness at presentation as defined by any of the following Respiratory rate greater than 80/min SaO2 less than 88% in room air Need for assisted ventilation Use of nebulized HS within previous 12 hours Previous enrollment in this study.
Key Trial Info
Start Date :
June 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT02253576
Start Date
June 1 2014
Last Update
November 13 2015
Active Locations (3)
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1
Victoria General Hospital
Victoria, British Columbia, Canada, V8Z 6R5
2
Royal Victoria Regional Health Centre
Barrie, Ontario, Canada, L4N 6S7
3
Southeastern Ontario Health Sciences Centre
Kingston, Ontario, Canada, K7L2V6