Status:
COMPLETED
Effect of Breaking up Prolonged Sitting on Metabolic Flexibility
Lead Sponsor:
University of Colorado, Denver
Conditions:
Health Behavior
Eligibility:
All Genders
19-45 years
Phase:
NA
Brief Summary
The investigators propose in this project to determine the effect of 3 days of frequent interruption of prolonged sitting on metabolic health in healthy overweight sedentary adults (n=24), as compared...
Detailed Description
Although public-health recommendations to engage in moderate-to-vigorous physical activity (at least 30min, 5 days / week) have been widely promulgated by the government, most people are physically in...
Eligibility Criteria
Inclusion
- overweight but weight stable (less than +/- 3kg over previous 6 months) male and female adults (n=24) will be recruited.
- age between 19-45 years old,
- a BMI of 27-33 kg/m2,
- inactive (≤ 1.5hr/wk of moderate-to-vigorous activity),
- sedentary (office employees who are spending more than 6hrs/day in sitting position) and
- English-speaking.
Exclusion
- any history of renal, cardiovascular or hepatic diseases,
- type 1 or 2 diabetes,
- cancer,
- pregnancy,
- smoking,
- consumption of drugs or alcohol (\>40g/d),
- any medications known to interfere with lipid or energy metabolism,
- known physical activity contraindications, or major illness/physical problems (acute or chronic) that may limit their ability to perform the walking activities and
- menopause (defined as no menses in the prior 6 months). The use of birth pill control will be accepted. Women are asked to avoid pregnancy until completion of Condition C.
Key Trial Info
Start Date :
October 8 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2017
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT02258438
Start Date
October 8 2014
End Date
September 1 2017
Last Update
April 30 2021
Active Locations (1)
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1
University of Colorado Hospital
Aurora, Colorado, United States, 80045