Status:
COMPLETED
Cardiovascular Effects of Apelin In Healthy Volunteers
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
NHS Lothian
Conditions:
Healthy
Eligibility:
All Genders
18-85 years
Phase:
EARLY_PHASE1
Brief Summary
Apelin is an endogenous peptide with physiological actions in the cardiovascular system. Apelin can modulate vasomotor tone and is a potent endogenous inotrope. In a series of clinical studies, we hav...
Detailed Description
Study Protocols Groups of 5 subjects will be assigned to receive one of three protocols. Protocol 1: Five healthy volunteers will be asked to attend the clinical research facility on a total of 4 oc...
Eligibility Criteria
Inclusion
- Healthy males or females \>18 years old
- Willing and able to complete an informed consent form
Exclusion
- Unable to give informed consent
- Pregnant or lactating at screening
- Use of any investigation product or device within 30 days prior to study.
Key Trial Info
Start Date :
November 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2015
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT02259686
Start Date
November 1 2014
End Date
May 1 2015
Last Update
June 1 2015
Active Locations (2)
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1
Clinical Research Facility University of Edinburgh
Edinburgh, United Kingdom, EH16 4SA
2
Wellcome Trust Clinical Research Facility. Western General Hospital
Edinburgh, United Kingdom, EH4 2XU