Status:
ACTIVE_NOT_RECRUITING
Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS
Lead Sponsor:
NYU Langone Health
Conditions:
Epilepsy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary study objective is to measure the electrical fields evoked by tDCS using subjects who have implanted intracranial electrodes as part of their evaluation for epilepsy surgery. The measureme...
Detailed Description
Noninvasive brain stimulation (NBS) represents a promising set of tools for neurotherapeutics and rehabilitation. In a literature search, NBS has been tested for over seventy neurologic and psychiatri...
Eligibility Criteria
Inclusion
- Subjects for this study will be recruited from patients undergoing routine intracranial electrode placement as part of the evaluation for surgical treatment of medically refractory epilepsy. Inclusion criteria include:
- Age ≥ 18 years
- Placement of intracranial electrode arrays (grid, strip and or depth electrodes) for seizure focus localization and/or mapping of eloquent cortex
- Able to provide written informed consent
- English-speaking patients only
Exclusion
- Cognitive impairment (Intelligence Quotient \<70)
- Facial or forehead skin breakdown that would interfere with surface electrode placement
- Contraindication to MRI
- Known adhesive allergy
- Space occupying intracranial pathology including brain tumor, ateriovenous malformation, cavernous malformation, prior surgical resection or significant encephalomalcia that would create unknown tissue inhomogeneity that cannot be accurately modeled.
- Subjects who have had an electrographic or clinical seizure within one hour prior to the stimulation procedure
Key Trial Info
Start Date :
November 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT02263274
Start Date
November 1 2013
End Date
June 1 2026
Last Update
May 1 2025
Active Locations (1)
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1
Neurology
New York, New York, United States, 11106