Status:
COMPLETED
Single Embryo TrAnsfeR of Euploid Embryo
Lead Sponsor:
Illumina, Inc.
Collaborating Sponsors:
Reprogenetics
Genesis Genetics
Conditions:
Infertility
Aneuploidy
Eligibility:
FEMALE
25-40 years
Phase:
NA
Brief Summary
The purpose of the current study is to evaluate the effect of preimplantation genetic screening (PGS) by next generation sequencing (NGS) compared to standard morphological assessment of embryos on pr...
Eligibility Criteria
Inclusion
- Patient undergoing IVF
- At least 2 blastocysts suitable for biopsy on day 5 or 6 of embryo development
Exclusion
- History of more than two prior implantation failure following IVF
- History of more than one miscarriage of viable pregnancy
- One or both partners known to be carrier(s) of a chromosomal abnormality
- Known genetic carrier couple and/or one or both partners carrier of a known autosomal dominant disorder
- Any other non-study related preimplantation genetic testing
- Use of donor oocytes
- Use of gestational carrier (surrogate or donor egg recipient).
- Severe oligospermia (\<1,000,000 sperm/ml); Surgical Sperm Retrieval for reasons other than post-vasectomy and CAVD
- Low ovarian reserve with (FSH) \>10 IU/L on day 2-4 of a prior menstrual cycle and/or (AMH) \<7 pmol/L (or \<1 ng/ml)
- Gender selection cycles
- Concurrent participation in another clinical trial
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2016
Estimated Enrollment :
661 Patients enrolled
Trial Details
Trial ID
NCT02268786
Start Date
September 1 2014
End Date
December 31 2016
Last Update
May 13 2020
Active Locations (38)
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1
Fertility Treatment Center
Tempe, Arizona, United States, 85284
2
HRC Fertility
Encino, California, United States, 91436
3
Acacio Fertility Clinic
Laguna Niguel, California, United States, 92677
4
HRC Fertility Pasadena
Pasadena, California, United States, 91105