Status:
WITHDRAWN
Testosterone Regulation of the Natriuretic Peptide System
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Hypertension
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The proposed study is a physiologic investigation of the effects of testosterone on the natriuretic peptide system. The hypotheses of the study are that testosterone administration will decrease natri...
Eligibility Criteria
Inclusion
- Men: aged 18 to 40 years, normal testosterone and free testosterone levels, no history of hypertension, and BMI between 18.5 and 25.
- Women: aged 18 to 40 years old, regular menstrual periods, negative pregnancy test, no oral contraceptives for ≥ 3 mos, no history of hypertension, BMI between 18.5 and 25.
Exclusion
- Antihypertensives, diuretics or insulin, diabetes mellitus, prior cardiovascular, abnormal liver or renal disease, history of cancer, atrial fibrillation, or abnormal sodium or potassium level.
Key Trial Info
Start Date :
February 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2016
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT02269072
Start Date
February 1 2015
End Date
February 1 2016
Last Update
October 19 2017
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