Status:

COMPLETED

The Immunogenicity and Safety of 2013-2014 Seasonal Trivalent Influenza Vaccine

Lead Sponsor:

Sinovac Biotech Co., Ltd

Conditions:

Influenza

Eligibility:

All Genders

6+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate the immunogenicity and safety of Northern hemisphere 2013-2014 seasonal trivalent inactivated influenza vaccine in 60 healthy infants aged 6-35 months old, 60 ...

Eligibility Criteria

Inclusion

  • For adults and seniors:
  • Healthy adults aged 18-60 years old, and healthy seniors aged \> 60 years old;
  • Without vaccination history of seasonal split influenza vaccine in the recent 3 years
  • No traveling plan during the study period of this trial;
  • Be able to understand and sign the informed consent;

Exclusion

  • Allergic to egg products or any ingredient of the study vaccine;
  • Fever, influenza or acute illness on the vaccination day;
  • Acute stage of chronic illness;
  • Malignant tumor;
  • Immunodeficiency, includes HIV infection;
  • Guillain-Barre syndrome;
  • Administration of live attenuated vaccine within the previous 14 days;
  • Administration of subunit or inactivated vaccine within the previous 7 days;
  • Planned to participate in any other clinical trial of drug or vaccine during this study;
  • Received immunesuppressive treatment within the previous month, or planned for such treatment during this study;
  • Pregnant, or planning pregnancy;
  • Axillary temperature \> 37.0℃;
  • Any other factors that, in the judgment of the investigator, is unsuitable for this study;
  • For infants:
  • Inclusion Criteria:
  • Healthy male or female aged between 6 and 35 months;
  • Full-term birth, birth weight 2,500 grams or more;
  • Provided birth certification or vaccination card
  • Parent or legal guardian is able to understand and sign the informed consent;

Key Trial Info

Start Date :

December 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2014

Estimated Enrollment :

182 Patients enrolled

Trial Details

Trial ID

NCT02269852

Start Date

December 1 2013

End Date

June 1 2014

Last Update

September 21 2015

Active Locations (1)

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1

Guzhen Center for Diseases Control and Prevention

Bengbu, Anhui, China