Status:
TERMINATED
A Pilot Study Into Health Pre and Post Treatment With Intravenous Aminophylline and Hydrocortisone in Severe Asthmatics
Lead Sponsor:
Royal Brompton & Harefield NHS Foundation Trust
Conditions:
Asthma
Eligibility:
All Genders
18-65 years
Brief Summary
This study focuses on severe asthmatics and their asthma symptoms. 40% of asthma patients continue to experience symptoms and up to 5% of these have difficult-to-control asthma despite continually imp...
Detailed Description
The participant will be involved in this project for approximately 3 - 4 weeks, depending on how long they usually come into hospital for, for clinical treatment. For 1 week they will wear a physical ...
Eligibility Criteria
Inclusion
- Age 18-65 years
- Diagnosis of severe asthma
- Confirmed therapy adherence via serum Prednisolone and cortisol levels
Exclusion
- Mild and moderate asthma
- Community acquired pneumonia
- Acute porphyria
- Pregnant and breast feeding women
- Patients hypersensitive to ethylenediamine or allergic to the theophyllines, caffeine and/or theorbromine.
- Patient with known hypersensitivity to components and in systemic fungal infection
- Patients that are being administered live attenuated vaccines.
Key Trial Info
Start Date :
June 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2015
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT02270827
Start Date
June 1 2014
End Date
February 1 2015
Last Update
October 28 2015
Active Locations (1)
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1
Royal Brompton Hospital
London, United Kingdom, sw3 6hp