Status:

COMPLETED

Comparative Study of Prophylactic Agent for Venous Thromboembolism After Total Knee Arthroplasty

Lead Sponsor:

Hanyang University Seoul Hospital

Conditions:

Venous Thromboembolism

Eligibility:

All Genders

Phase:

PHASE2

Brief Summary

The purpose of this study is to compare the efficacy of two prophylactic agent(aspirin 300mg/day and rivaroxaban 10mg/day) for venous thromboembolism after total knee arthroplasty.

Detailed Description

1. Thromboprophylactic regimens Aspirin®(acetylsalicylic acid, AA, Bayer) 300mg/day or Xarelto® (rivaroxaban, factor Xa-inhibitor, Bayer) 10mg/day will be randomly(according to the sequence of operati...

Eligibility Criteria

Inclusion

  • all patients undergone primary total knee arthroplasty

Exclusion

  • renal insufficiency, contrast allergy, simultaneous bilateral TKA, hemorrhagic disorder, sever liver disease

Key Trial Info

Start Date :

October 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2016

Estimated Enrollment :

156 Patients enrolled

Trial Details

Trial ID

NCT02271399

Start Date

October 1 2014

End Date

February 1 2016

Last Update

February 19 2016

Active Locations (1)

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Department of Orthopaedic Surgery, Hanyang University, College of Medicine

Seoul, South Korea, 133-792