Status:
COMPLETED
Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Lead Sponsor:
Ente Ospedaliero Cantonale, Bellinzona
Conditions:
Fluid Overload
Anesthesia; Adverse Effect, Spinal and Epidural
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Aim of this study is to determine whether Inferior Vena Cava analyzed by trans-thoracic echocardiography is an effective method to guide titrated fluid repletion in non critical patients, in order bot...
Detailed Description
The setting is standard spinal anesthesia and corresponds to our first arm of the study, used as the control sample and statistical reference. During the induction phase, the patient is fitted with no...
Eligibility Criteria
Inclusion
- both sexes
- grater than 18 year old
- requiring spinal anesthesia
- classified according to American Society of Anesthesiology (ASA) level as 1, 2 or 3
Exclusion
- patients required invasive blood pressure monitoring (arterial/pulmonary catheter, thermodilution catheter),
- patients show signs of pre-procedural hypotension (defined as two measurements of systolic arterial pressure less than 80 mmHg and/or mean arterial pressure less than 60 mmHg),
- patients unable to give informed consent to language barriers, mental retard or any reduction in own ability to understand or give their informed consent,
- patient in which is not possible to perform spinal anesthesia for patient's refusal or technical difficulties in sampling,
- patients with International Normalized Ratio (INR) greater than 1.5 and/or activated Partial Thrombin Time in therapeutic range (more than 1.5 - 2 times the patient's normal values) and/or anti-factor X activity in therapeutic range
- patients with thrombocytopenia less than 50 G/l.
Key Trial Info
Start Date :
May 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT02271477
Start Date
May 1 2014
End Date
December 1 2014
Last Update
August 31 2017
Active Locations (1)
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1
Ospedale Regionale di Bellinzona e Valli (ORBV) - Sede Bellinzona
Bellinzona, Switzerland, 6500