Status:

RECRUITING

Immune Response in Patients With Hepatitis B and C Infection

Lead Sponsor:

Mid and South Essex NHS Foundation Trust

Collaborating Sponsors:

Foundation for Liver Research

Conditions:

Hepatitis B

Hepatitis C

Eligibility:

All Genders

18-70 years

Brief Summary

Using peripheral blood mononuclear cells (PBMC) and serum collection from HBV and HCV infected patients in a number of different immunological assays, the investigators hope to identify any changes in...

Detailed Description

Hepatitis B virus (HBV) and C (HCV) are the leading causes of liver disease worldwide. Approximately 400 million people worldwide are chronically infected with HBV world wide and it is estimated that ...

Eligibility Criteria

Inclusion

  • Chronic Hepatitis B patients At all stages of infection Treatment naive and previously treated Longitudinal samples from patients treated with antiviral agents and interferon
  • Chronic Hepatitis C patients All genotypes - treatment naive and previously treated Longitudinal samples from patients treated with interferon and STATIC therapy

Exclusion

  • Coinfection with HIV Coinfection with hepatitis delta Excessive alcohol use Autoimmune liver disease Metabolic liver disease

Key Trial Info

Start Date :

August 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT02275221

Start Date

August 1 2013

End Date

December 1 2024

Last Update

January 12 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Basildon Hospital

Basildon, Essex, United Kingdom, SS16 5NL