Status:
COMPLETED
Effect of SNPs in the BCMO1 Enzyme
Lead Sponsor:
Newcastle-upon-Tyne Hospitals NHS Trust
Collaborating Sponsors:
Newcastle University
DSM Nutritional Products, Inc.
Conditions:
Beta-carotene Bioavailability
Vitamin A Deficiency
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
Summary: Chronic intake of foods low in vitamin A (retinol) and provitamin A forming an unbalanced diet with little variety is common in young individuals in the United Kingdom (UK) population and ca...
Eligibility Criteria
Inclusion
- Healthy individual.
- Female.
- Between 18 and 45 years of age.
- Caucasian.
- BMI between 18 and 30 kg/m2.
- Subject willing and able to give written informed consent.
Exclusion
- Smoking.
- Diabetes.
- Gastrointestinal diseases.
- Renal and hepatic diseases.
- Hyperlipidaemia.
- Preformed dietary retinol intake above 60% of reference nutrient intake (RNI) values.
- Recreational drug use.
- Multi-vitamin consumption.
- Pregnancy.
- Menopause.
- Allergy or sensitivity to study products or ingredients.
- Blood donation 3 months prior to screening.
- Participation in other clinical study 4 weeks prior to study start.
- Suspected inability or unwillingness to comply with study procedures.
Key Trial Info
Start Date :
April 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2014
Estimated Enrollment :
85 Patients enrolled
Trial Details
Trial ID
NCT02276014
Start Date
April 1 2012
End Date
September 1 2014
Last Update
October 6 2015
Active Locations (1)
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1
Newcastle NIHR Clinical Research Facility, Royal Victoria Infirmary
Newcastle upon Tyne, Tyne & Wear, United Kingdom, NE1 4LP