Status:
COMPLETED
Activated MMP-8 as Diagnostic Test for Periodontitis
Lead Sponsor:
Goethe University
Conditions:
Generalized Chronic Periodontitis
Eligibility:
All Genders
18+ years
Brief Summary
Background: Untreated periodontal disease may influence general health. However, how may a physician who is not trained in periodontal probing detect untreated periodontitis? Activated matrix metallop...
Detailed Description
.The hypotheses behind this study were: \- The aMMP-8 test discriminates between individuals with and without untreated generalized chronic periodontitis Thus, sensitivity and specificity of a chair...
Eligibility Criteria
Inclusion
- At least18 years of age
- Clinical diagnosis of generalized moderate or generalized severe ChP
- At least 5 teeth present per quadrant
- After application to the ethics committee: written informed consent
Exclusion
- Requirement of systemic antibiotics for measures that may cause transitory bacteraemia (e.g. pocket probing)
- Nonsurgical or surgical periodontal treatment within the last 12 months prior to PerioMarker® test
- Systemic or topical subgingival antibiotics within the last 6 months prior to PerioMarker® test
- Anti-inflammatory medication (e.g. non-steroidal anti-inflammatory drugs) during the last 3 months prior to PerioMarker® test
Key Trial Info
Start Date :
September 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2014
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02280122
Start Date
September 1 2012
End Date
February 1 2014
Last Update
July 13 2015
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