Status:
COMPLETED
Alterations in Muscle After Total Knee Arthroplasty
Lead Sponsor:
University of Colorado, Denver
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
50-75 years
Phase:
NA
Brief Summary
The overall goals of this work are: 1) to elucidate alterations in gene expression and downstream protein synthesis 2 weeks after Total Knee Arthroplasty (TKA) to better explain quadriceps muscle atro...
Eligibility Criteria
Inclusion
- 50 to 75 years of age
- Scheduled for unilateral TKA at University of Colorado Hospital
- Diagnosed with osteoarthritis
- Cognitive status that allows patients to consistently comprehend and repeat back directions regarding the details of the study
Exclusion
- Neurological, vascular or cardiac problems that significantly limit function
- BMI \> 35
- Testosterone supplementation
- Pregnancy
- Anticoagulant therapy
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 9 2020
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT02281877
Start Date
October 1 2014
End Date
March 9 2020
Last Update
June 9 2021
Active Locations (2)
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1
Univeristy of Colorado Anschutz Medical Campus
Aurora, Colorado, United States, 80045
2
University of Colorado School of Medicine
Aurora, Colorado, United States, 80045