Status:
COMPLETED
Spanish Retrospective Study to Evaluate the Efficacy and Safety of Targeted Therapies After Pazopanib as First-line Therapy
Lead Sponsor:
Spanish Oncology Genito-Urinary Group
Conditions:
Metastatic Renal Cell Carcinoma
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this retrospective observational study was to analyze the effect of targeted therapies administered as second-line treatment after failure of pazopanib as well as increase the amount of...
Eligibility Criteria
Inclusion
- Patients ≥ 18.
- Metastatic renal cell cancer of any histology.
- Patients treated with pazopanib for metastatic cell renal cancer outside the context of clinical trials (clinical practice) in Spanish centers from 1 April 2011 until 30 June 2014. shall be included all patients who received pazopanib as first-line treatment in each participating center, whether had experienced treatment failure with pazopanib or were still in first-line treatment. The inclusion of patients who are also allowed received cytokine as first-line treatment followed by pazopanib as well as patients who received sunitinib as first-line treatment and have changed pazopanib for toxicity or intolerance, provided they have not received more a cycle of sunitinib.
- Centers that agree to participate must commit to: · Include all patients meeting the inclusion criteria to reduce by possible selection bias. Because it supplies only pazopanib Hospital pharmacy service (not outside hospitals), the identification of patients will be performed at the hospital pharmacy records in each participating center.
Exclusion
- Patients who received pazopanib in clinical trials or treatment second line, with the exceptions noted above.
- Patients with the diagnosis and / or treatment of malignancies of importance other than Cell renal cancer.
Key Trial Info
Start Date :
October 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT02282579
Start Date
October 1 2014
End Date
April 1 2015
Last Update
April 26 2018
Active Locations (34)
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1
Hospital Son Espases
Palma de Mallorca, Mallorca, Spain
2
Hospital Clínic de Barcelona
Barcelona, Spain
3
Hospital Vall d' Hebron
Barcelona, Spain
4
Hospital San Pedro de Alcántara
Cáceres, Spain