Status:

WITHDRAWN

TMS Electrochemotherapy for Glioblastoma Multiforme

Lead Sponsor:

University of Aarhus

Conditions:

Glioblastoma

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The proposed project aims to develop novel electrochemotherapeutic treatment of glioblastoma multiforme (GBM). Standard treatment has limited effect on survival and quality of life. Electrochemotherap...

Eligibility Criteria

Inclusion

  • Newly diagnosed and histologically confirmed glioblastoma multiform
  • MGMT gene methylation
  • If age \< 70, eligibility to comply with the Stupp radio chemotherapy regimen
  • If age \> 70, eligibility for stand alone chemotherapeutic treatment
  • Ability to comply with the proposed TMS treatment
  • Use of validated anti-conception for fertile female participants in concordance with guidelines provided by the Danish Health and Medicines Authority

Exclusion

  • Pregnancy or nursing
  • Other conditions that may contraindicate the use of transcranial magnetic stimulation
  • Implanted pacemaker or metal contraindicating MRI-scan

Key Trial Info

Start Date :

January 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 31 2019

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT02283944

Start Date

January 1 2015

End Date

May 31 2019

Last Update

September 20 2021

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