Status:
COMPLETED
The Effect of Intranasal Vasoconstrictor Medications on Hemodynamic Parameters: A Randomized Double-blind, Placebo-controlled Trial.
Lead Sponsor:
Mayo Clinic
Conditions:
Epistaxis
Blood Pressure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Nosebleeds (epistaxis) are a frequent cause of emergency department visits, reportedly inciting 1 in 200 visits. They are most common in those less than ten and older than seventy, often occurring in ...
Eligibility Criteria
Inclusion
- Healthy volunteers over the age of eighteen that have been recently dismissed from the Emergency Department at Mayo Clinic Hospital, Saint Marys Campus.
- We will recruit a convenience sample of 100 patients from the Emergency Department who have completed their Emergency Department evaluation and treatment and are being discharged to home with non-painful conditions.
Exclusion
- We will exclude persons under the age of eighteen
- Vulnerable populations (pregnant patients and prisoners)
- Those with an allergy to any of the study agents
- Those with acute pain
- Those using antihypertensive or antiarrhythmic agents
- Those with significant cardiopulmonary comorbidities (namely history of arrhythmia, coronary artery disease, hypertension, and heart failure)
- Those with concomitant use of Monoamine oxidase A (MAO) Inhibitors
- Those with a diagnosis of angle closure glaucoma or benign prostatic hyperplasia (BPH)
- Those with a history of cerebrovascular disease
- As well as those with a history of previous nasal surgery or known nasal anatomic abnormalities.
Key Trial Info
Start Date :
November 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 22 2017
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT02285634
Start Date
November 1 2014
End Date
December 22 2017
Last Update
October 2 2018
Active Locations (1)
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1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905