Status:
COMPLETED
18-FDG PET/CT Imaging and Clinical Decisions in Infective Endocarditis
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Infective Endocarditis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to assess the impact of 18-FDG positron emission tomography (PET)/computed tomography (CT) imaging in the management of patients with suspected or proven IE in detecting c...
Detailed Description
Introduction: Infective endocarditis (IE) is a rare disease, often difficult to diagnose with a high mortality rate. Extra-cardiac manifestations, which can occur in 30 to 80% of cases, impact the ou...
Eligibility Criteria
Inclusion
- Subjects aged ≥ 18 years
- Presenting IE "Duke-Li definite - Duke-Li possible" or strong suspicion of IE "Duke-Li not definite or possible, with initiation of IE antibiotic therapy".
- Transthoracic or transesophageal ultrasound performed.
- A stable clinical condition which does not require immediate surgery or contraindicate patient mobilization
- Absence of cardiac surgery for the current IE episode
- Covered by the French health insurance system
- Having given and signed the written study informed consent to the study.
Exclusion
- Patient having already had a 18-FDG PET/CT in the current episode
- Contraindication to perform a 18-FDG PET/CT
- Early prosthetic valve IE (cardiac surgery within last 2 months)
- Inability to understand the information form
- Pregnant or lactating woman.
- Cardiac surgery between inclusion and 18-FDG PET/CT
- Participation to any clinical trial including 18-FDG PET/CT
Key Trial Info
Start Date :
April 17 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2017
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT02287792
Start Date
April 17 2015
End Date
January 1 2017
Last Update
August 8 2025
Active Locations (1)
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1
Bichat Claude Bernard Hospital
Paris, France, 75018