Status:
UNKNOWN
Renal Function Assessment in the Elderly Using Plasma Creatinine Assay and Lean Body Mass Measurement
Lead Sponsor:
University Hospital, Strasbourg, France
Conditions:
Renal Function
Eligibility:
All Genders
75+ years
Phase:
NA
Brief Summary
Glomerular filtration rate (GFR) is the recommended parameter to assess renal function. The reference technique to measure GFR (clearance of a glomerular agent) is not commonly used. Instead, estimati...
Eligibility Criteria
Inclusion
- Inclusion criteria :
- age of 75 years of more
- origin from Western Europe or North Africa
- covered by social health insurance
- general health condition allowing transportation and ambulatory procedures during one day
- Exclusion criteria :
- ascitis, oedema or third compartment
- fast change in body weight (more than 5% in less than one week)
- eGFR \< 30 mL/min/1.73 m² (using MDRD formula)
- legal concerns: prisoners, guardianship, lack of health insurance, failure to consent
- intake of drugs that interfere with creatinine tubular secretion
- cimetidine
- trimethoprim
- intake of drugs that interfere with creatinine assay
- calcium dobesilate
- hydroxocobalamin
- N-ethylglycine
- phenindione
- lidocaine
- inability to lie during 10 minutes without moving
- patients who are bedridden, hemiplegic or highly dependent on others
- any health condition that, in the investigator's opinion, could rapidly (\< 1 week) vary the extracellular volume or GFR (these is voluntarily left open to the investigator because it is hardly possible to make an exhaustive list here)
Exclusion
Key Trial Info
Start Date :
November 3 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 2 2022
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT02288663
Start Date
November 3 2014
End Date
November 2 2022
Last Update
June 14 2021
Active Locations (1)
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1
Hôpitaux Universitaires de Strasbourg
Strasbourg, France, 67098